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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

不过,接受调查的经济学家们预期2016年期间将出现略高的增长率和显著更高的通胀率。
影片直接来自真实的Bling Ring帮,2008年,他们10个月的赃物飚升了300万美元。电影列出的所有名人都是这个团伙真实的受害者。团伙成员声称,是社会对这些名人私生活的痴迷鼓励了他们。无论动机如何,《炫富帮》都很好地提醒了人们,要时不时与媒体拉开距离。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 广州:租赁量或呈短期回升态势
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

“尽管我本质上是一名工程师和分析人员,但迄今为止我所做过的最重要的决定都与此无关,它们永远是基于直觉,”他去年在曾就读MBA的杜克大学(Duke University)对一名采访者表示。
Her mother discovered the debits on Jan 30, China Central Television reported.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 群雄逐鹿的民宿市场 究竟有多美?
Open Access Perspective

Soft matter science and the COVID-19 pandemic

23岁的古纳尔?优素福(Gunal Youssouf)是Teach First人,她加入了普华永道(PwC)英国分公司的管理咨询毕业生项目。优素福表示,在Teach First的两年让她有机会在不用花钱攻读传统资格证书的情况下尝试教学工作。

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 楼市局部现回暖 市场分化仍持续
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

去年12月,包括中国商务部、中国央行在内的四个政府部门表示,将收紧对房地产、酒店、影城、娱乐业、体育俱乐部等领域的“非理性”对外投资项目的审查。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

单词mortgage 联想记忆:
2. Get a Belstaff coat and blue scarf. The coat cost about 1350 pounds. It's got good twirl for those dramatic moments in life.
201312/270513.shtml
We will strengthen the prevention and control of water and soil pollution.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 人才抢夺战背后的隐忧
Perspective

Trends and targets in antiviral phototherapy

库尼斯在去年的榜单上排名第九。
在3月2号,北韩政府网站我们民族之间警告北韩将对任何气球投放展开"炮弹和导弹的攻击,而不只是几下枪击"。
The Lost Tomb
“图特摩斯三世是埃及新王朝最重要的法老之一。他使埃及在迦南完成了从一个地域性王国向洲际大帝国的质变。”“圣殿山筛选项目”的联合发起人和总负责人Gabriel Barkay如是说。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

I give all my love to you this New year.值此佳节,献上我对你所有的爱。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

借助于Artnet等公布拍卖结果的数据库,如今购买艺术品的富豪非常清楚要想在早期绘画大师的作品上获利非常困难。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
From the themed collection: 水星家纺IPO终止审查
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

其他的欧洲国家生活成本在增长,排名有进步。伦敦上升了5个名次,并且进入前十。
['steibl]

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

激情、毅力和积极的心态,是创业成功的关键。培养这些特质要有天赋和一些小技巧。
单词affection 联想记忆:

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

stress
指数:93.6

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

现在达洛伊西奥还不负责管理他的收入。他坚称说,我太年轻了,还不懂如何发挥其价值。我没有房贷,我才17。对我来说100英镑就是个大数目了,这就是我对钱的大致概念。尽管他无法对Summly的售价置评,但当我逼问他未来打算如何支配的时候,他说他在考虑以后也许可以用所发之财来做一名天使投资人。在他身边,似乎没人觉得这份钱会毁掉他或者他会挥霍钱财浪费人生。戴安娜说,孩子很踏实,很有冲劲儿,他不会停止奋斗的。
这台叫做IP-BOX的设备可以破解运行iOS 7或者更老版本的iPhone,通常它需要6秒到17小时来破解iPhone的四位锁屏密码。英国《每日邮报》购买了这台设备,并在6小时内破解了苹果iPhone 5c的锁屏密码。该密码破解设备运行在iOS 9系统上的版本将会在本月晚些时候出现。
Despite an abortive attempt in August to devalue the renminbi — a move that rocked global markets and was quickly abandoned by Beijing — China’s trade-weighted exchange rate was 8.5 per cent stronger in September than a year earlier, making Chinese exports less competitive.
"The rate of college students who have had sexual experiences using condoms is less than 40 percent," said Han Mengjie, director of Chinese Center for Disease Control and Prevention.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

4.Sex and the City Caused a Rush on Cupcakes

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Soyabeans which are trading above $10 a bushel are expected to remain strong, while dairy prices are also expected to rise during 2017 as demand steadily increases, said the bank.
Full marks to Prince George for giving the patronising high-five of the Canadian prime minister the eye.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

当小李子上台领取奖杯时,制片人哈维·韦恩斯坦兴奋地拍拍他的背,全场观众起立为他喝彩。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

Wang Dengfeng, director of the Physical Education, Health and Art Department under the Ministry of Education (MOE) and Vice Chairman of the China Football Association, was quoted as saying that football experts are designing curriculums for more than 360 training programs in primary and secondary schools.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

2. The 'Dad bod' is so hot right now
沃伦·巴菲特自2014年以来再次排名第二,净资产由去年的608亿美元增加到756亿美元。
Despite the seemingly extensive target vetting on May 7 the Chinese embassy in Belgrade was struck by five Joint Directed Attack Munition satellite-guided bombs delivered by U.S. Air Force B-2 Spirit bombers. Three Chinese journalists—Shao Yunhuan of Xinhua and Xu Xinghu and his wife Zhu Ying of the Guangming Daily—were killed in the attack. Twenty other Chinese nationals were injured five seriously.
人事工作类

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Morocco is home to nine UNESCO World Heritage Sites, mainly ancient towns and old city ruins, making it a decent choice for history lovers.
这一次,湖人队处境不错,而且不需要赶着去做什么事,给他们点时间,看看他们到底会怎样。用这样的防守质量他们很难进入季后赛,但是这并不是这个赛季的重点。
Farewell to Don and his perfect suits, to Peggy and her plaids, to Joan and her jewel tones and sheaths.
The UK and France are the two powerhouses of business education in Europe. Nearly half of the schools listed are from either the UK (20) or France (19). French MiMs outperform UK programmes in terms of ranking, salary ($55,000 versus $49,000) and student numbers (9,000 versus 1,200). However, UK MBAs outdo French programmes in terms of numbers (18 schools in this ranking versus five) and student numbers (1,900 versus 1,300) though not in terms of salary ($115,000 versus $137,000).
怎么玩吉他

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

(实际上,在过去三年的节日假期里,捷蓝航空公司绝对不是航班起飞延误最糟糕的航空公司。这项殊荣要授予Comair公司,这是达美航空公司经营地区航线的公司。不过该公司在2012年假日季节开始前停业,因此我们没有让这家公司上榜。)
根据美国国会预算办公室(Congressional Budget Office)的数据,税收增加与支出削减将2013年的经济增速拉低了约1.5个百分点。许多预测人士认为,2014年财政因素对经济增速的拖累幅度将是2013年的三分之一或更低。牛津经济研究院(Oxford Economics)的美国经济学家达科(Gregory Daco)称,今年政治方面的确定性更高。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

Stripping out price, volumes of Chinese imports in October fell a more modest 2.6 per cent from a year earlier, according to estimates from Oxford Economics.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

当年的荷兰金融市场固然没有今天的任何科技,但他们的很多做法都和今天的交易员一样。投资者们买入证券,有时会用买入的股票质押获得贷款。用今天的话说,他们基于保证金买入股票。贷款机构为了自身安全,会要求一个超出贷款金额一定百分比的“折幅”,质押现金或证券。如果证券价格下跌超过一定幅度,贷款机构会要求投资者交出更多资金,与“折幅”保持一致。如果投资者拿不出追加保证金,贷款机构有权将证券平仓,收回贷款额。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

Hope you enjoy the happiness of New Year and all the trimmings.
Every point we think we've reached where James cannot be better than he has been, he then blows past it like a poor center switched onto him. What will be discussed most is his all-encompassing skill, but this is also a testament to the work that James puts in. You can mock all those Instagram videos he puts up, but those are the real reason he's still able to do this; James has never cheated the game, not a day in his life, and the result is incomparable performance night in and night out.
包括圣诞购物季在内,第四季度的电脑出货量共计7190万台。IDC方面表示,这是自IDC公司开始追踪该数据以来最大的降幅。
A shortage of qualified supply chain managers right now, especially in global companies that must coordinate far-flung operations, can be traced to two factors.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

他表示,目前腾讯旗下的游戏和直播应用不需要实名注册,不过腾讯公司正在考虑建立一个平台,以方便家长监护孩子的行为。
"There are 1,400 individuals who are involved in the departures for jihad,for terrorism, in Syria and in Iraq," Valls told BFMTV.
平板电脑的病毒出现。
谢丽尔·布恩·艾萨克斯,学院理事会主席

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

新兴市场投资者不需要被提醒美联储(Fed)对新兴市场资产的重要性——不是吗?
When the federal government shuttered in October, Starbucks (SBUX, Fortune 500)CEO Howard Schultz refused to sit on the sidelines while businesses everywhere suffered. Instead, Schultz wrote a petition calling on his peers to rally together and put pressure on Congress to come to an agreement.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

There’s nothing worse than a boss who says one thing and does another, and nothing better than one who keeps his word. Just as managers must trust their team, employees must trust their boss to have their best interests at heart。
谁也不愿意自己的家门口整天闹个不停。
但是美国加州公务员退休基金(Calpers)的高级投资组合经理兼全球治理主管安妮?辛普森(Anne Simpson)却相信,库克的道德立场不仅仅是种姿态。她说:“他对作秀技巧的漠视自有其魅力。蒂姆?库克将苹果这种优雅和卓越的理念应用到这些新的领域。”加州公务员退休基金是苹果的重要股东。
曲道奎表示:“随着机器人正逐渐扩至几乎所有领域,我国机器人制造商应当了解自身和外资品牌间的差距,利用中国机器人的蓬勃发展并学习国外经验,以帮助我国由世界最大的机器人市场成长为机器人制造强国。”
The economy has registered a slower but stable performance with good momentum for growth.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

But top managers at companies in the fields of scientific research and technology services saw their pay decrease by 4.2%.
我是一个封闭的人
Leila Janah

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

adj. 传统的
当时,Spielman正在耶路撒冷Emek Tzurim国家公园橄榄山的斜坡上检查泥土。突然就注意到了这个小小的矩形物件。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

斯坦福大学的Zhenan Baohas 研发出了一种具备超弹性、超耐性和超敏感的材料,能够作为未来发展人工皮肤的基础。以前,人们也研究过生化皮肤,但是Baohas的材料比以前研发出来的更具敏感性。它带有有机转换物质和一层弹性材料,保证它在不被破坏情况下的延展性。另外,这种材料带有一系列的太阳能电池元件,可以自动充电。
We will ensure workplace safety and people's lives.
“我们会根据天气谨慎考虑投送的时间和地点,但这些都不会公开,”脱北者Park Sang-Hak说道,他曾经领导过一系列的气球投送运动。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

12. Scientists modify photosynthesis to boost crop yield
俄罗斯总统普京说,无论谁在明年的美国总统大选中胜出,他都希望改善与美国的关系。
1. The remote control belongs to me for the whole month.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

['?p?reit]

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

一名校友表示:我们被迫远离了安逸,但获得了独特的体验。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

他们两个自称拥有着世界上最大的两个粉丝基础。但是周日晚上,在伦敦温布利SSE竞技场上举行的2017年欧洲音乐大奖中,Shawn Mendes夺得桂冠, Taylor Swift在她参选的五个奖项中纷纷落选。
2016年全国硕士研究生招生考试周日结束后不久,教育部即接到考研试题泄露的举报。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

3. 《聚焦》(Spotlight),导演:汤姆·麦卡锡(Tom McCarthy)。
随着《喜羊羊与灰太狼》大电影第二部《喜羊羊与灰太狼之虎虎生威》的上映,这部空前火爆的国产动画再度成为众人关注的焦点。你知道怎么用英文介绍《喜羊羊与灰太狼》么?I
lace
3)告诉我更多吧:这句话的潜台词:“洗耳恭听。”这是开启话匣子的终极法宝!当你向对方敞开心扉、表达好奇的时候,对方一定会做出善意的回应。而且,谁不喜欢听好听的呢?如果你真的对对方所说的话感兴趣,或许你就能促成一次富有成效的交流。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

回归白人占统治地位的社会,实施排外的国民身份认同,这样的事情不太可能发生。移民一旦停止,肯定会损害西方国家的经济;如果大举驱逐已经到达的移民,肯定会引起社会与道德上的损失。那些看似来“插队”的人群其实是在寻觅一个机会,加入到一个长久以来把他们拒之门外的进程中来。
The second half of this year should see a similar number of IPOs, making a total of about 120 cases in 2016 with about 60 billion to 80 billion yuan in financing volume, Lyn predicted.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

上海复旦大学社会发展与公共政策学院院长彭希哲周二告诉环球时报,在产业结构升级的过程中,劳动密集型产业搬离都市圈,是导致这一人口变迁的最主要原因之一。
6.癌症死亡率

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Cross talk “Do Not Blame Me” (Cao Yunjin and Liu Yuntian)

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

n. 文件,公文,文档
2017年度国家公务员考试上周日开考,大学生自主创业和"玉兔"月球车等最近的热门话题进入国考考题。
Anyway, it's nice to see that LeBron has filled into his monster physique nicely in the past nine years.
The UK’s Warwick Business School recorded the best progression at the top, moving up from 16th to ninth place, while the Shanghai Advanced Institute of Finance (Saif), based at JiaoTong University, enjoys the bestprogression overall, jumping from 28th to 14th place.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

财新经济学家何帆表示:“这表明宏观经济已进一步趋稳,经济结构正在改善。今后必须协调财政政策和货币政策,尽可能避免大规模刺激。”
17. Most Complex Hurdle As of Dec. 7, seven out of 20 domestic top-grossing movies released this year had female-driven stories, according to the website Box Office Mojo. By contrast, five out of 20 female-driven stories topped the international market, which accounts for some 70 percent of the industry’s revenue. This may look bad, but the numbers appear marginally better than they have in recent years.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 佛山住房公积金利用率高
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

1. 热爱自己的事业。
Friends count too
黄记泳表示,去年赴韩旅游的中国游客超过800万人,同比增长36%。他还表示,甚至在韩国政府宣布部署萨德之后,该数字也曾继续上升。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

并且第四座航站楼已经竣工,将于2017年下半年投入使用。
店长马克·斯特罗恩说,开发这种设备旨在帮助那些忘记自己锁屏密码的iPhone用户进入被锁在手机上的照片或通讯录。斯特罗恩在香港第一次看到这台设备,他表示,在最一开始大家都对其能否起作用持怀疑态度。但随着时间的推移,这台设备一次又一次的证明了自己。
In 2016, China's box-office experienced a shock correction, with growth plummeting to just 3.7 percent from a roaring 48 percent rate in 2015.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

追踪中国服务业增长的财新PMI指数将于下周二发布。
With China now not only “fully integrated”, but perhaps starting to retreat from this position as it brings more of its supply chain onshore, unless Africa can succeed in following China’s path, he adds: “I think we are going back now to a situation where we don’t think there is any particular reason for trade to grow faster than GDP.”

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

5. Broadcaster
46岁的姚振华以深圳为大本营,在房地产上赚取了第一桶金。但他的净财富之所以能在一年内增长约8倍,凭借的是他旗下的宝能集团(Baoneng Group)进军保险业和随后对房地产业竞争对手万科(Vanke)展开“突袭”。万科在中国多座城市拥有业务。
巴黎法新社-1400法国人已经加入圣战组织或者打算这么做,总理ManuelValls周一说。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

This marks the first time that Google has topped the list since 2011.
会。美国政府在垂直合并案上已有数十年没赢过。据美国司法部(Department of Justice)自己的审查指导原则,像时代华纳这样的内容所有者与AT&T这样的分销商之间的“垂直合并”,远不如水平合并那么令人担忧。与此同时,Facebook、亚马逊(Amazon)、Netflix和谷歌(Google)这四巨头(合称FANG,取每家名称首字母)如今主宰了数字娱乐版图,这使得政府的如下论点更难以站住脚:两家传统媒体公司的合并,会从根本上改变竞争态势。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Unlike many young girls who are starstruck by celebrities, Maddie claims that she keeps a cool head at events like the Grammys because she sees herself as a star, so needs to act accordingly.
指数: 97.8
Makers of processed food, soda and fast food see markets in the developing world as their greatest growth opportunities. At the same time, obesity rates and weight-related illnesses are on the rise in developing countries. An ongoing series of articles examined the interaction of these two trends, starting with cases in Brazil, Ghana and Colombia. Taken together, these stories reveal “a new global food order, and a new health crisis.”

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

The Shanghai Stock Exchange saw 26 IPOs, while its Shenzhen counterpart saw 15 IPOs of small-and-medium-sized enterprises and 20 start-up companies.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

提供公务员考试培训的教育机构中公网校的数据显示,报名首日共有31220人通过审核,超过去年同期的2.5万人。
The recession may be over, but the job market recovery is lagging way behind. And experts say the situation may get worse before it gets better.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Sonneborn, who lives in Bristol, Vermont, with his parents and younger sister, Julia, 11, is seeking the Democratic nomination.
11月房价环比平均下跌0.5%。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 石材行业如何淘汰落后产能
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

他说,“油价将波动上行。”
11月18日

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

阅读成功的商业案例。吸收史蒂夫o乔布斯等成功创业者以及《创智赢家》(Shark Tank)提供的知识财富。一份成功的商业计划书不需要长篇累牍。10页纸的商业计划书既便于理解,又足以包含你要开始实施的所有内容。
According to a 2014 survey it conducted, 86 per cent of respondents who finished the two years said they were taking action to end educational in-equality through their work and 65 per cent outside of their work.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

豆瓣网友“Amy”称:“他们是神仙。除了谈情说爱,就不能干点别的吗?”

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

The Caixin-sponsored composite PMI for November came in at 50.5, the first time it had broken through the 50-mark separating contraction from expansion since July.
我们就是要打造开放的高地、投资的热土,和世界共享发展机遇。
Dachis: JetBlue started the year with some tough moments (a pilot’s panic attack gave them a rough start), but customer satisfaction and excellent social service during the busy holiday travel season carried the brand to success in 2012.
BrandZ表示,这些品牌靠近国内市场,这帮助它们从全球品牌手中夺取市场份额,它们还在新地区赢得市场份额。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

After 'Gravity' and 'American Hustle,' my picks are in alphabetical order:

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 北京56家银行暂停首套房贷
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

20. 对电影爱好者的最佳建议。8月学者韦勒·温斯顿·迪克森(Wheeler Winston Dixon)发出了警告:“如果你上亚马逊,看到什么精彩的黑白电影卖三美元,或者其他什么外国电影和鲜为人知的电影,赶快买下来,因为它就要绝版了,他们不会再出版它们了。”成千上万这种VHS格式的电影不会被做成DVD格式或蓝光格式,迪克森警告说。而下载的美丽新世界(又名电子销售)明年将是好年头。
A hero is one that doesn't want to bea hero. A hero is a one with all the possibility to make the choice but takethe responsibility of the moment. And it's really something hero has got to do.For example, in 9/11 some of the plane's passengers fought with the terrorists.In Fukushima's radiation leak, some people went and tried to fix the nuclearplant and died. But they have to do it. They are heroes. They don't try to beheroes. They take responsibility and try to do what is right.
And, thanks to Artnet and other databases that list auction results, wealthy people who buy art have become all too aware of how hard it is to make a profit on old masters.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Its corporate customers value the school’s flexibility and ability to innovate. “We have developed a programme which is co-delivered with an experimental learning provider,” commented one client responding to the FT survey. “Iese has been a true partner in this process and our business has benefited with an energised and prepared executive bench.”
1. “暂时没有名字的泡沫”引发30年来的最大规模崩盘

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
From the themed collection: 广联达助力建筑企业钢筋细化管理
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Stanford's Zhenan Baohas has developed a super-flexible, super-durable, and super-sensitive material that can be the basis for future synthetic skin. People have tried developing synthetic skin before, but Baohas's material handles touch sensitivity better than any predecessor. It contains organic transistors and a layer of elastic, letting it stretch without taking damage. And it's self-powered—this skin contains a series of elastic solar cells.
The accountancy firm in charge of the Oscars results has apologized after Warren Beatty and Faye Dunaway were handed the wrong results card when announcing the Best Picture award and incorrectly announced La La Land as the winner rather than Moonlight.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Though many people associate Porsche with pure performance cars, in recent years the brand has expanded their lineup to include the Panamera, a luxury large car shown here, as well as the Cayenne and Macan SUVs. According to most reviewers, the Panamera not only lives up to the performance heritage of the Porsche’s brand, but also coddles occupants with an opulent interior and the connectivity features today’s luxury buyer demands.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

I agreed with Craig and Neil immediately that Ellen is the ideal host for this year’s show. We’re looking forward to an entertaining, engaging and fun show.
Many are less than impressed by the cheesy indulgence, with the New York Daily News speaking to one dietitian who blasted the lack of nutritional value in the pizza's most expensive ingredient: the Ecuador-imported gold flakes.
ar一再,rog要求-一再要求-傲慢的arrow ant:一个想射箭的蚂蚁-傲慢自大的

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

The 25 most common passwords have been released by Splashdata which makes password management applications.
The low reading was driven by a fall in the production component, whereas the forward-looking new orders component increased for a sixth straight month.
但是,那些宣称不大可能会消失。阿拉巴马州大学亨茨维尔校区的大气科学家约翰·R·克里斯蒂(John R. Christy)以怀疑全球变暖的严重性而知名,他在一次采访中指出,2014年的记录只比以前年度的创纪录温度高出百分之几度,完全是在全球温度测量值的误差范围之内。克里斯蒂说,“自20世纪末,气温并没有太多变化,一直处于较暖的稳定水平。”
The Amsterdam crisis began when a Dutch group known as the Seppenwolde syndicate made a big, contrarian bet on the shares of East India Company. Those shares had plunged in 1771 mainly because of losses in Bengal, but the company kept paying high dividends and covered up its shortfalls by borrowing money. Convinced that East India shares would quickly rebound, the Seppenwolde group aggressively bought them on margin. But instead of rebounding, the shares fell even further after the company slashed its dividend.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

库克必须在开放与围绕其产品开发的神秘感间寻找平衡。在苹果内部已经有关于另一个秘密项目的传闻,它规模与iPhone或Apple Watch相当,正在整个库比提诺招兵买马。
2017年度国家公务员考试上周日开考,大学生自主创业和"玉兔"月球车等最近的热门话题进入国考考题。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

被氦气顶起来的泡沫穿过图形模板。
52% of the world lived in extreme poverty in 1981. This number dropped down by 21% in 2010, as 721 million fewer people no longer live in absolute poverty.
其他的欧洲国家生活成本在增长,排名有进步。伦敦上升了5个名次,并且进入前十。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

3.Sit in the Front Row
关于“白”的定义总是存在一定程度的不稳定性。美国的爱尔兰与意大利移民,英国的犹太人,都曾一度被排除在白人多数群体之外,如今却因为他们的种族特征,同样被视为白人主流的一部分。与此同时,尽管犹太人也是白皮肤,特朗普的某些支持者们还是会把他们视为外来者,这些人经常在社交网络上散布反犹太的网络米姆。

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